Improving the Ring‐opening Polymerization of l‐Lactide Using n‐Butyl Lithium with Various Bidentate Ligands |
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| Authors: | Hsuan‐Ying Chen Yen‐Tzu Huang Jaya Kishore Vandavasi Yu‐Hsieh Chen Chia‐Hao Kuei |
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| Affiliation: | 1. Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;2. Institute of Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C.;3. Division of Urology, Department of Surgery, Cardinal Tien Hospital and School of Medicine Fu‐Jen, Catholic University, New Taipei, Taiwan, R.O.C. |
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| Abstract: | ![]()
A series of bidentate ligands were examined to improve the catalytic activity of l ‐lactide (LA) polymerization by using n‐butyl lithium and BnOH. For LA polymerization, n‐butyl lithium with tetraisopropyl methylenebis(phosphonate) (L8 ) showed the greatest catalytic activity but with poor controllability of the polymer molecular weight. The polydispersity indices (PDIs) could be improved without BnOH addition, but Mn GPC was much different from the Mn Cal . 1H NMR spectra confirmed that the cyclized PLA was obtained, thus implying that active chain‐end mechanisms were operative in LA polymerization. |
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| Keywords: | Lithium
l
‐Lactide Ring‐opening polymerization |
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