Synthesis of imidazo[4,5-a]acridones and imidazo[4,5-a]acridines as potential antibacterial agents |
| |
| Authors: | Mohammad Rahimizadeh Mehdi Pordel Mehdi Bakavoli Zahra Bakhtiarpoor and Ala Orafaie |
| |
| Institution: | (1) Department of Chemistry, School of Sciences, Ferdowsi University of Mashhad, 91775-1436 Mashhad, Iran;(2) Department of Biology, School of Sciences, Ferdowsi University of Mashhad, 91775-1436 Mashhad, Iran; |
| |
| Abstract: | Abstract New imidazo4,5-a]acridone derivatives were synthesized from the rearrangement of 3H-imidazo4′,5′:3,4]benzoc]isoxazoles. New imidazo4,5-a]acridines were obtained from the reaction of imidazo4,5-a]acridones in boiling POCl3. All of these compounds exhibited antimicrobial activities comparable to streptomycin as reference drug. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
