Dimeric ortho‐palladated homoveratrylamine as an efficient homogeneous catalyst for copper‐free Sonogashira cross‐coupling reaction |
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| Authors: | Abdol R Hajipour Hannaneh Rahimi Fatemeh Rafiee |
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| Institution: | 1. Department of Chemistry, Isfahan University of Technology, , Isfahan, 84156 IR Iran;2. Department of Neuroscience, University of Wisconsin Medical School, , Madison, WI, 53706‐1532 USA |
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| Abstract: | The catalytic activity of ortho‐palladated Pd{C6H2(CH2CH2NH2)‐(OMe)2,3,4}(m‐Br)]2, a complex of homoveratrylamine in the copper‐free Sonogashira coupling reaction has been investigated. This complex is a catalyst that is efficient, stable and non‐sensitive to air and moisture in the Sonogashira reaction. In this homogeneous catalytic system, various aryl halides were efficiently coupled with phenylacetylene in mostly moderate to good yields in N‐methylpyrrolidone at 100 °C under copper‐free conditions. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | Sonogashira reaction catalyst ortho‐palladated complex internal alkynes |
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