Non‐aggregated boron–fluorine derivatives with photodynamic activity |
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| Authors: | Liang Yao Feijun Dan Qiong Cao Miaofu Mao Shuzhang Xiao |
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| Institution: | Hubei Key Laboratory of Natural Products Research and Development, College of Chemistry and Life Science, China Three Gorges University, , Hubei Yichang, 443002 People's Republic of China |
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| Abstract: | Novel non‐aggregated boron–fluorine derivatives with large Stokes shift were facilely synthesized and characterized. These dyes show moderate absorptive coefficients and intense fluorescence emission, and excellent photo‐stability in solvents and also in solid state. According to X‐ray single‐crystal analysis, non‐covalent intermolecular interactions provide a rigid structure, which inhibits aggregate formation. These non‐aggregated dyes can generate singlet oxygen under light irradiation, which makes them good candidates for photodynamic therapy. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | BOPIM solid emission photodynamic therapy singlet oxygen |
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