New Furostanol Glycosides from the Roots of Digitalis ciliata Trautv. |
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| Authors: | Ether Kemertelidze Alexander Skhirtladze Markus Ganzera |
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| Institution: | 1. Iovel Kutateladze Institute of Pharmacochemistry, 36 P. Sarajishvili st., 0159 Tbilisi, Georgia, (phone: +995‐595372745;2. fax: +995‐322379255);3. University of Innsbruck, Institute of Pharmacy, Pharmacognosy, Innrain 80?–?82, AT‐6020 Innsbruck |
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| Abstract: | Three new furostanol glycosides, named ciliatasides A, B, and C ( 1 – 3 , resp.), have been isolated from the roots of Digitalis ciliata, along with two known furostanol glycosides. The structures of the new compounds were identified as (2α,3β,5α,14β,25R)‐26‐(β‐D ‐glucopyranosyloxy)‐2‐hydroxyfurost‐20(22)‐en‐3‐yl β‐D ‐glucopyranosyl‐(1→2)‐β‐D ‐glucopyranosyl‐(1→3)]‐β‐D ‐galactopyranoside ( 1 ), (2α,3β,5α,14β,22R)‐26‐(β‐D ‐glucopyranosyloxy)‐2‐hydroxy‐22‐methoxyfurost‐25(27)‐en‐3‐yl β‐D ‐galactopyranosyl‐(1→2)‐β‐D ‐xylopyranosyl‐(1→3)]‐β‐D ‐glucopyranosyl‐(1→4)‐β‐D ‐galactopyranoside ( 2 ), and (2α,3β,5α,14β,22R,25R)‐26‐(β‐D ‐glucopyranosyloxy)‐2,22‐dihydroxyfurostan‐3‐yl β‐D ‐glucopyranosyl‐(1→2)‐β‐D ‐glucopyranosyl‐(1→3)]‐β‐D ‐galactopyranoside ( 3 ). |
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| Keywords: | Digitalis ciliata Furostanol glycosides Glycosides Ciliatasides A – C |
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