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Computer-aided optimization of stepwise gradient and multiple-development thin-layer chromatography
Authors:W Markowski  E Soczewinski
Institution:(1) Department of Inorganic and Analytical Chemistry, Medical Academy, Staszica 6, 20081 Lublin, Poland
Abstract:Summary Equations for the final RF values for mobile phase gradient development and gradient multiple development are presented. Computer simulations of gradient development for both modes of thin-layer chromatography are discussed for the preliminary optimization of gradient programs.
Keywords:Thin-layer chromatography  Gradient of mobile phase  Gradient multiple development  Automated multiple development  Optimization by computer simulation
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