|
|||||
|
|
| Computer Simulation of Gd(III) Speciation in Human Interstitial Fluid | |
| 引用本文： | Jin Ping WANG,Hai Yuan ZHANG,Chun Ji NIU*,Jia Zuan NI Key Laboratory of Rare Earth Chemistry and Physics,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022. Computer Simulation of Gd(III) Speciation in Human Interstitial Fluid[J]. 中国化学快报, 2003, 14(2) |
| 作者姓名： | Jin Ping WANG Hai Yuan ZHANG Chun Ji NIU* Jia Zuan NI Key Laboratory of Rare Earth Chemistry and Physics Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 |
| 作者单位： | Jin Ping WANG，Hai Yuan ZHANG，Chun Ji NIU*，Jia Zuan NI Key Laboratory of Rare Earth Chemistry and Physics，Changchun Institute of Applied Chemistry，Chinese Academy of Sciences，Changchun 130022 |
| 基金项目： | financial support of this work (Project Nos. 29890280，29971029). |
| 摘 要： | The study on biological effects of rare earths is of great importance because more and more rare earths enter into the environment and human body via food chain etc.1, 2 The research on rare earth speciation is a key to understand distribution, metabolism and biological effects of rare earths. As a continuation of our research on rare earth speciation in human body3,soluble and insoluble speciations of Gd(III) in human interstitial fluid were studied in this work. Almost all the stability … |
Computer Simulation of Gd(III) Speciation in Human Interstitial Fluid |
|
| Jin Ping WANG,Hai Yuan ZHANG,Chun Ji NIU,Jia Zuan NI. Computer Simulation of Gd(III) Speciation in Human Interstitial Fluid[J]. Chinese Chemical Letters, 2003, 14(2) | |
| Authors: | Jin Ping WANG Hai Yuan ZHANG Chun Ji NIU Jia Zuan NI |
| Abstract: | The speciation and distribution of Gd(III) in human interstitial fluid was studied by computer simulation. Meantime artificial neural network was applied to the estimation of log ?values of complexes. The results show that the precipitate species, GdPO4 and Gd2(CO3)3, are the predominant species. Among soluble species, the free Gd(III), [Gd(HSA)] , [Gd(Ox)] and then the ternary complexes of Gd(III) with citrate are main species and [Gd3(OH)4] becomes the predominant species at the Gd(III) total concentration of 2.2?0-2mol/L. |
| Keywords: | Computer simulation gadolinium(III) speciation human interstitial fluid. |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |