| Exploring Feasibility for Application of Luminescent CdTe Quantum Dots Prepared in Aqueous Phase to Live Cell Imaging |
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| 作者姓名： | Ji Fang WENG Xing Tao SONG Liang LI Hui Feng QIAN Ke Ying CHEN Xue Ming XU Cheng Xi CAO Ji Cun REN |
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| 作者单位： | [1]College of Chemistry ＆ Chemical Engineering [2]College of Life Science ＆ Biotechnology, Shanghai Jiaotong University, Shanghai 200240 |
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| 摘 要： | Due to the quantum confinement, semiconductor quantum dots (QDs) show some unique and fascinating optical properties, such as, sharp and symmetrical emission spectra, high quantum yield (QY), good chemical and photo-stability. These excellent optical prop…
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| 关 键 词： | CdTe量子点 碲化镉 水合成 HUVEC UEA-1 细胞成像 |
| 收稿时间： | 2005-11-23 |
Exploring Feasibility for Application of Luminescent CdTe Quantum Dots Prepared in Aqueous Phase to Live Cell Imaging |
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| Ji Fang WENG Xing Tao SONG Liang LI Hui Feng QIAN Ke Ying CHEN Xue Ming XU Cheng Xi CAO Ji Cun REN.Exploring Feasibility for Application of Luminescent CdTe Quantum Dots Prepared in Aqueous Phase to Live Cell Imaging[J].Chinese Chemical Letters,2006,17(5):675-678. |
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| Authors: | Ji Fang WENG Xing Tao SONG Liang LI Hui Feng QIAN Ke Ying CHEN Xue Ming XU Cheng Xi CAO Ji Cun REN |
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| Abstract: | This paper explored the feasibility for the application of luminescent CdTe quantum dots prepared in aqueous phase to live cell imaging. The highly luminescent CdTe quantum dots (QDs) were first prepared in aqueous phase, and then were covalently coupled to a plant lectin (UEA-1), as a fluorescent probe. After incubating with of human umbilical vein endothelial cells (HUVECs), the QD probe with UEA-1 was able to specifically bind the corresponding cell receptor. The good cell images were obtained in live cells using laser confocal scanning microscopy. We predict that QDs prepared in water phase will probably become an attractive alternative probe in cellular imaging and bio-labeling. |
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| Keywords: | CdTe quantum dots aqueous synthesis HUVEC UEA-1 |
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