Synthesis and Reactions of Some New Pyrrolylfuro[2,3‐d]Pyrimidines and Pyrrolopyrazinofuropyrimidines |
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Authors: | SH. A. Abdel‐Mohsen SH. H. Abdel‐Hafez A. A. Geies |
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Abstract: | 5‐Amino‐4‐methyl‐2‐phenyl‐6‐substitutedfuro[2,3‐d]pyrimidines ( 2a‐c ) were reacted with 2,5‐dimethoxytetrahydrfuran to afford the pyrrolyl derivatives 3a‐c . Compound 3a was chosen as intermediate for the synthesis of poly fused heterocycles incorporated furopyrimidines moiety 4–11 . Some of the synthesized compounds were screened for their antibacterial and antifungal activities. |
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Keywords: | Pyrrolylfuro[2,3‐d]pyrimidines Oxadiazoles Pyrazines Thiazoles Antimicrobial activity |
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