New vesicle formation upon oleate addition to preformed vesicles |
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Authors: | Chungcharoenwattana Suparpun Ueno Masaharu |
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Institution: | Faculty of Phamaceutical Sciences, Toyama Medical and Pharmaceutical University. |
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Abstract: | The size distribution of new vesicles formed after addition of oleate in different forms to preformed egg yolk phosphatidylcholine (EggPC) vesicles was studied by gel exclusion chromatography. The addition of oleate to preformed vesicles resulted in the formation of new small vesicles. Fission of preformed vesicles incorporated by oleate and partial solubilization of the vesicles by addition of oleate in micellar form were involved in the process of the new small vesicle formation. |
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