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Distributed analysis of simultaneous EEG-fMRI time-series: modeling and interpretation issues
Authors:Fabrizio Esposito  Adriana Aragri  Tommaso Piccoli  Gioacchino Tedeschi  Rainer Goebel  Francesco Di Salle
Affiliation:1. Department of Neuroscience, University of Naples “Federico II”, 80131 Naples, Italy;2. Department of Cognitive Neuroscience, Maastricht University, Maastricht, The Netherlands;3. Department of Neurological Sciences, Second University of Naples, Naples, Italy;4. Neurological Institute for Diagnosis and Care “Hermitage Capodimonte”, Naples, Italy;5. Department of Neurosciences, University of Pisa, Pisa, Italy
Abstract:
Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) represent brain activity in terms of a reliable anatomical localization and a detailed temporal evolution of neural signals. Simultaneous EEG-fMRI recordings offer the possibility to greatly enrich the significance and the interpretation of the single modality results because the same neural processes are observed from the same brain at the same time. Nonetheless, the different physical nature of the measured signals by the two techniques renders the coupling not always straightforward, especially in cognitive experiments where spatially localized and distributed effects coexist and evolve temporally at different temporal scales.
Keywords:EEG   fMRI   Distributed source modeling   Working memory   Default-mode
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