One pot synthesis of imidazo[2,1-b]thiazoles and benzo[d]thiazolo[3,2-a]imidazoles |
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| Authors: | Niyaz A Mir Tariq A Shah Sarfaraz Ahmed M Muneer Nigam P Rath Musheer Ahmad |
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| Institution: | 1. Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India;2. Department of Chemistry and Biochemistry and Center for Nanoscience, University of Missouri-St. Louis, St. Louis, MO 63121, USA;3. Supramolecular Lab, Department of Chemistry, Indian Institute of Technology, Kanpur 208016, India |
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| Abstract: | A series of imidazo2,1-b]thiazole and benzod]thiazolo3,2-a]imidazole analogues were synthesized by stirring an equimolar mixture of dibenzoylacetylene with imidazole/thiazole derivatives in toluene or acetonitrile at room temperature. The products were generated in good yields and characterized by standard analytical techniques such as IR, 1H NMR, 13C NMR and mass spectrometry. The structure of products 19, 20, 22, 24 and 25 were also unambiguously confirmed by single crystal X-ray analysis. |
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| Keywords: | Imidazo[2 1-b]thiazole Benzo[d]thiazolo[3 2-a]imidazole Dibenzoylacetylene |
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