A two-step,single pot procedure for the synthesis of substituted dihydropyrazolo-pyrimidines |
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| Authors: | Jake R. Zimmerman Brian J. Myers Samantha Bouhall Allison McCarthy Olivia Johntony Madhuri Manpadi |
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| Affiliation: | 1. Ohio Northern University, Department of Chemistry and Biochemistry, 525 South Main Street, Ada, OH, USA;2. Drury University, Department of Chemistry, Springfield, MO, USA |
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| Abstract: | In this study, we report a two-step, one pot tandem microwave-assisted reaction of 3-formylchromones with aminopyrazoles followed by a tin-free radical addition. A library of alkyl substituted dihydropyrazolopyrimidines was prepared using this new process. |
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| Keywords: | Dihydropyrazolopyrimidine Tin-free radical 3-Formyl chromone Tandem reaction Amino pyrazole |
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