Isolation,characterization, and NMR spectroscopic data of indole and oxindole alkaloids from Mitragyna speciosa |
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| Authors: | Zulfiqar Ali Hatice Demiray Ikhlas A Khan |
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| Institution: | 1. National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA;2. Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA;3. Ege University, Faculty of Science, Biology Department, Izmir 35100, Turkey |
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| Abstract: | A new indole alkaloid, 7β-hydroxy-7H-mitraciliatine (1) and a new oxindole alkaloid, isospeciofoleine (2) together with nine known alkaloids were isolated from Mitragyna speciosa and characterized by NMR, CD, and MS spectroscopic data analyses. The 1H and 13C NMR spectroscopic data of isospeciofoline (3), isorotundifoline (4), paynantheine (5), and 3-isopaynantheine (6) were also reported for the first time. |
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| Keywords: | Mitragyna speciosa Rubiaceae Indole/oxindole 7β-Hydroxy-7H-mitraciliatine Isospeciofoleine |
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