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l-Proline catalyzed efficient and convenient synthesis of substituted 2H-chromenes by three-component reaction
Authors:L. Chandrasekhara Rao  H.M. Meshram  N. Satish Kumar  N. Nageswara Rao  N. Jagadeesh Babu
Affiliation:1. Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India;2. Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India
Abstract:
A convenient and efficient method is described for the synthesis of alkoxy substituted 2H-chromens by l-proline catalyzed reaction of salicylaldehydes with diketone in alcohol. The method is applicable for various substituted salicylaldehydes and aliphatic as well as benzylic alcohols.
Keywords:Salicylaldehyde   Pentane-2   4-Dione   2H-Chromens   l-Proline
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