Recent developments in the synthesis of zoanthamine alkaloids |
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| Authors: | Fumihiko Yoshimura Keiji TaninoMasaaki Miyashita |
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| Institution: | Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan |
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| Abstract: | This review provides a compilation of the most recent synthetic approaches and total syntheses of zoanthamine alkaloids, which are structurally unique heptacyclic marine natural products that display a range of interesting biological activities. This review is focused on synthetic methodologies for the construction of the three adjacent quaternary asymmetric carbon atoms on the cyclohexane ring (C-ring) of these compounds. The literature covered in this review dates from 2008 to the end of 2013. |
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| Keywords: | Zoanthamine alkaloids Total synthesis Quaternary asymmetric carbon atom Aminoacetal |
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