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A mesoporous silica/fluorinated alcohol adduct: an efficient metal-free,three-component synthesis of indazolophthalazinetrione heterocycles using a reusable nanoporous/trifluoroethanol adduct (SBA-15/TFE)
Authors:Sadegh Rostamnia  Esmail Doustkhah
Affiliation:Organic and Nano Group (ONG), Department of Chemistry, Faculty of Science, University of Maragheh, PO Box 55181-83111, Maragheh, Iran
Abstract:The channels of mesoporous (SBA-15) represent a straightforward reactor for the rapid synthesis of indazolophthalazinetrione skeletons via three-component coupling reactions in 2,2,2-trifluoroethanol. The solid SBA-15 and TFE could be recovered and reused. The present method carries the advantage of being performed under neutral conditions and requires no activation or modification of the substrates.
Keywords:Multicomponent reaction   Trifluoroethanol   SBA-15   Indazolophthalazinetriones
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