Synthesis of novel benzopyrano[3,2-c]coumarins via tandem base promoted nucleophilic substitution and intramolecular electrophilic aromatic cyclization
1. Department of Chemistry, Sankar Foundation Research Institute, Naiduthota, Visakhapatnam 530047, India;2. X-ray Crystallography Division, Indian Institute of Chemical Technology, Hyderabad 500076, India
Abstract:
Efficient and facile synthesis of 7H-benzopyrano[3,2-c]coumarins has been achieved by mild base promoted reaction of 4-chloro-3-formylcoumarin with diversely functionalized resorcinols. All the products were obtained as pure precipitates from the reaction mixture and the structure of the product was confirmed by X-ray analysis.