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Synthesis of novel benzopyrano[3,2-c]coumarins via tandem base promoted nucleophilic substitution and intramolecular electrophilic aromatic cyclization
Authors:Satyanarayana Reddy Jaggavarapu  Anand Solomon Kamalakaran  Jagadeesh Babu Nanubolu  Venkata Prasad Jalli  Sravan Kumar Gangisetty  Gopikrishna Gaddamanugu
Affiliation:1. Department of Chemistry, Sankar Foundation Research Institute, Naiduthota, Visakhapatnam 530047, India;2. X-ray Crystallography Division, Indian Institute of Chemical Technology, Hyderabad 500076, India
Abstract:
Efficient and facile synthesis of 7H-benzopyrano[3,2-c]coumarins has been achieved by mild base promoted reaction of 4-chloro-3-formylcoumarin with diversely functionalized resorcinols. All the products were obtained as pure precipitates from the reaction mixture and the structure of the product was confirmed by X-ray analysis.
Keywords:Benzopyrano coumarins   Resorcinol   4-Chloro-3-formylcoumarin   Tandem   X-ray crystallography
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