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A facile synthesis of benzo[b][1,4]thiazepine derivatives by palladium acetate catalyzed reaction
Authors:Partha Pratim Kaishap  Kommuri ShekarraoPallabi Saikia  Sanjib Gogoi  Romesh C Boruah
Institution:Medicinal Chemistry Division, North-East Institute of Science and Technology, Jorhat 785006, Assam, India
Abstract:The preparation of steroid/nonsteroid fused benzob]1,4]thiazepines and 2-arylsubstituted benzob]1,4]thiazepines is described from Pd(OAc)2 catalyzed reaction of steroidal/nonsteroidal β-halovinyl aldehydes and 2-aminothiophenols in DMF under heating condition.
Keywords:Benzo[b][1  4]thiazepine  Steroid  Palladium acetate  β-Bromovinyl aldehyde  2-Aminothiophenol
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