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Hupermine A,a novel C16N2-type Lycopodium alkaloid from Huperzia phlegmaria
Authors:Yusuke Hirasawa  Yuri Kato  Chin Piow Wong  Nahoko Uchiyama  Yukihiro Goda  A Hamid A Hadi  Hapipah Mohd Ali  Hiroshi Morita
Institution:1. Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan;2. National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan;3. Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
Abstract:A novel C16N2-type Lycopodium alkaloid consisting of a quinolizidine with a 6-dimethylaminohexyl side chain, hupermine A (1), was isolated from the club moss of Huperzia phlegmaria, and the structure and relative stereochemistry were elucidated on the basis of spectroscopic data.
Keywords:Hupermine A  Huperzia phlegmaria  Lycopodium phlegmaria  Lycopodium alkaloid
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