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Smart Soft‐Templating Synthesis of Hollow Mesoporous Bioactive Glass Spheres
Authors:Yunqi Li  Dr. Bishnu Prasad Bastakoti  Prof. Yusuke Yamauchi
Affiliation:1. World Premier International (WPI) Research Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1–1 Namiki, Tsukuba, Ibaraki 305‐0044 (Japan) http://www.yamauchi‐labo.com;2. Faculty of Science and Engineering, Waseda University, 3‐4‐1 Okubo, Shinjuku, Tokyo 169‐8555 (Japan)
Abstract:Hollow bioactive glass spheres with mesoporous shells were prepared by using dual soft templates, a diblock co‐polymer poly(styrene‐b‐acrylic acid) (PS‐b‐PAA) and a cationic surfactant cetyltrimethylammonium bromide (CTAB). Hollow mesoporous bioactive glass (HMBG) spheres comprise the large hollow interior with vertical mesochannels in shell, which realize large uptake of drugs and their sustained release. The formation of hydroxyapatite layer on the surface of HMBG particles shows the clear evidence for promising application in bone regeneration.
Keywords:bioactive glass  hollow spheres  mesoporous materials  polymeric micelles  surfactants
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