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Host–Guest Chemistry of a Bis‐Calix[4]pyrrole Derivative Containing a trans/cis‐Switchable Azobenzene Unit with Several Aliphatic Bis‐Carboxylates |
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| Authors: | Grazia Cafeo Franz H. Kohnke Giovanni Mezzatesta Aldo Profumo Camillo Rosano Antonino Villari Andrew J. P. White |
| Affiliation: | 1. Dipartimento di Scienze Chimiche, Università di Messina viale F. Stagno d'Alcontres 31, 98166 Messina (Italy);2. Current address: Dipartimento di Ingegneria Elettronica, Chimica, e Ingegneria Industriale, Università di Messina, Contrada Di Dio (S. Agata), 98166 Messina (Italy);3. IRCCS A.O.U. San Martino‐IST, Istituto Nazionale per la Ricerca sul Cancro, Largo R. Benzi 10, 16132 Genova (Italy);4. Dipartimento di Scienze del Farmaco e Prodotti per la Salute, Università di Messina, Polo Universitario Viale SS. Annunziata SNC, 98168 Messina (Italy);5. Chemical Crystallography Laboratory, Department of Chemistry, Imperial College London, South Kensington, London SW72AZ (UK) |
| Abstract: | The azobenzene unit used as a photochemically and thermally switchable linker in the assembly of a bis‐calix[4]pyrrole receptor provides a means to modulate the binding of bis‐carboxylates of significant biological importance in cancer research. Conversely, the complexation of different bis‐anionic guests has significant kinetic effects on both the photochemical and thermal trans/cis isomerization of the azobenzene unit. |
| Keywords: | anion binding azocompounds calixpyrroles carboxylates host– guest systems |