Metallophosphites as umpolung catalysts: the enantioselective cross silyl benzoin reaction |
| |
| Authors: | Linghu Xin Potnick Justin R Johnson Jeffrey S |
| |
| Affiliation: | Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA. |
| |
| Abstract: | Carbonyl polarity reversal (umpolung) has been realized employing metallophosphites as catalysts. As a result, nonenzymatic asymmetric cross silyl benzoin reactions have been achieved, giving optically active silyl ether-protected benzoin adducts. The reaction is general with respect to aryl, alkyl, and heterocyclic substrates with good to excellent yields and good to excellent enantioselectivities. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
