|
|||||
|
|
A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions |
|
| Authors: | Olsen Jacob A Banner David W Seiler Paul Obst Sander Ulrike D'Arcy Allan Stihle Martine Müller Klaus Diederich François |
| Affiliation: | Laboratorium für Organische Chemie, ETH-H?nggerberg, HCI, 8093 Zürich, Switzerland. |
| Abstract: | |
| Keywords: | fluorine inhibitors medicinal chemistry molecular recognition structure elucidation thrombin |
| 本文献已被 PubMed 等数据库收录！ | |