Simultaneous Chiral SeparationUsing a Combinatorial Molecular Imprinting Phase

Molecular imprinting chiral stationary phase against Cbz-L- Serine (Cbz- L-Ser) and Cbz-L-Alaine (Cbz-L-Ala) were prepared utilizing acrylamide 2-vinylpyridine as combined basic functional monomers. Cross-selectivity was used to obtain simultaneous chiral separations of Cbz-DL-Ser and Cbz-DL-Ala by connecting two columns packed with Cbz-L-Ser and Cbz-L-Ala imprinted chiral stationary phase, respectively.