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2-Allyloxy/propargyloxypyridines: synthesis,structure, and biological activity
Authors:E. V. Babaev  Y. I. Koval  V. B. Rybakov  E. G. Paronikyan  G. M. Stepanyan  R. G. Paronikyan  Sh. Sh. Dashyan  S. A. Rzhevskii  I. A. Shadrin
Affiliation:1.Department of Chemistry,M. V. Lomonosov Moscow State University,Moscow,Russian Federation;2.A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry,National Academy of Sciences of the Republic of Armenia,Yerevan 26,Armenia
Abstract:The alkylation (allylation and propargylation) of 3-cyano-6-dialkylamino-2-pyridones containing a d-annulated ring occurs at the oxygen atom. The structures of the starting compounds and their alkylation products were determined by X-ray diffraction. The neurotropic and antimicrobial activity of alkylation products was examined.
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