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| 癌细胞培养的热化学测量 | |
| 引用本文： | 徐桂端,谢昌礼,孙达远,屈松生,肖海光,胡解郁.癌细胞培养的热化学测量[J].物理化学学报,1988,4(4):337-339. |
| 作者姓名： | 徐桂端 谢昌礼 孙达远 屈松生 肖海光 胡解郁 |
| 作者单位： | Department of Chemistry; Wuhan University;Department of Virology; Wuhan University |
| 摘 要： | 我们用微量量热学方法对小鼠乳腺癌细胞(MA 782/5 S-1801)在离体培养状态下进行了热化学测量,测得单个癌细胞此状态下代谢的发热功率_平均为35.1 pW/cell。以此为对照加入某种抑制剂(BNA)对癌细胞某代谢环节进行抑制时,进行同样的测量,发现该癌细胞代谢发热功率明显下降,平均结果为23.2pW/cell。这些结果对进一步研究癌细胞代谢的机理及筛选抗癌药剂将有一定的意义。 |
| 收稿时间： | 1988-01-25 |
| 修稿时间： | 1988-04-02 |
MEASUREMENT OF THERMOCHEMISTRY OF CANCER CELL CULTURE |
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| Xu Guiduan,Xie Changli,Sun Dayung,Qu Songsheng, Xiao Haiguang,Hu Jieyu.MEASUREMENT OF THERMOCHEMISTRY OF CANCER CELL CULTURE[J].Acta Physico-Chimica Sinica,1988,4(4):337-339. |
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| Authors: | Xu Guiduan Xie Changli Sun Dayung Qu Songsheng Xiao Haiguang Hu Jieyu |
| Institution: | Department of Chemistry; Wuhan University;Department of Virology; Wuhan University |
| Abstract: | Using microcalorimetric method, we have determined the metabolic output power of Mouse Mammary Adenocarcinoma cell (MA 782/5S-8101) at the culture medium, the average value is 35.1 pW/cell. As cross reference, using the same method the output power of this cancer cell was determined at medium which contain inhibitor, the results show clearly that the output power was inhibited obviously, the correspondent average value is 23,2pW/cell. |
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