X-ray structural investigation of gossypol and its derivatives. XXVIII. Separation of the dilactol tautomeric form of gossypol hexamethyl ether into individual stereoisomers and evaluation of their clathrate-forming capacity

All three possible stereoisomers of gossypol hexamethyl ether in the dilactol tautomeric form have been separated with the aid of fractional crystallization and have been identified crystallographically. These stereoisomers have been subjected to x-ray stuctural investigation, and their configurations and clathrateforming properties have been determined.Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 62 70 71. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 682–686, September–October, 1995. Original article submitted February 6, 1995.