Supramolecular Chirality: Chiral hydrogen-bonded supermolecules from achiral molecular components

Chiral supermolecules may be obtained from suitable achiral molecular constituents associated through a dissymmetrizing interaction mode. This is the case for the supermolecules I–IV formed by hydrogen-bonding association between the achiral complementary components 1a , b and 2a , b , c . The crystal structures of the supermolecular pairs I–III and of the homochiral aggregate of two ternary supermolecules IV have been determined. The structural data are discussed.