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依诺沙星与铁配合物的合成、表征及其生物活性
引用本文:张淑凤,张兆林,王海杰. 依诺沙星与铁配合物的合成、表征及其生物活性[J]. 化学通报, 2012, 0(6): 569-571
作者姓名:张淑凤  张兆林  王海杰
作者单位:沧州医学高等专科学校;沧州市传染病医院;沧州市第二中学
摘    要:
由水热法合成了依诺沙星铁配合物,用固体培养基平板药敏试验方法测定了配合物的体外抗菌活性。结果表明,合成的依诺沙星铁配合物对金黄色葡萄球菌、肺炎链球菌、绿脓杆菌、白色念珠菌都具有抗菌活性,但只有对金黄色葡萄球菌和绿脓杆菌的抗菌活性强于配体本身。

关 键 词:依诺沙星  配合物  抗菌活性

Preparation and Antibacterical Activity of the Fe Complex of Enoxacin
Zhang Shufeng,Zhang Zhaolin,Wang Haijie. Preparation and Antibacterical Activity of the Fe Complex of Enoxacin[J]. Chemistry, 2012, 0(6): 569-571
Authors:Zhang Shufeng  Zhang Zhaolin  Wang Haijie
Affiliation:1Cangzhou Medical College;2Cangzhou Infectious Disease Hospital; 3Cangzhou 2nd Middle School,Cangzhou Hebei 061001)
Abstract:
The titled complex was synthesized by hydrothermal method,and the in vitro antibacterial activities of the as-synthesized complex for Staphylococcus aureus,Streptococcus pneumoniae,Pseudomonas aeruginosa,Candida albicans were investigated by susceptibility testing using the solid medium plate.The results showed that the Fe complex of enoxacin exhibits antibacterial activity,but the activities were stronger than that of the ligand itself against Staphylococcus aureus and Pseudomonas aeruginosa only.
Keywords:Enoxacin  Complex  Antibacterial activity
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