Sulphonamide Residues in Italian Surface and Drinking Waters: A Small Scale Reconnaissance |
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Authors: | D Perret A Gentili S Marchese A Greco R Curini |
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Institution: | (1) Laboratorio Chimico per la Sicurezza, Dipartimento di Chimica, Università ``La Sapienza', Piazzale Aldo Moro 5, P.O. Box 34, Posta 62, 00185 Roma, Italy |
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Abstract: | The occurrence of antibiotics in the aquatic environment is an important emerging issue due to potential adverse effect of these compounds on ecosystem and human health. For a correct environmental risk assessment there is a need for appropriate analytical methods for monitoring antibiotic residues in a variety of water matrices. This paper describes a method for the determination of eleven sulphonamide compounds in surface and drinking waters using solid-phase extraction and liquid chromatography-tandem mass spectrometry. Recoveries of the analytes in both surface and drinking water matrices at different fortification levels, always exceed 87%; the limits of quantification in surface water samples are between 0.005 and 0.021 µg L?1 depending on the compound, and the interday method precision is less than 12%. Matrix effects were evaluated in drinking and surface water samples. The method has been applied to a small scale reconnaissance of river, lake, mineral and municipal water samples; results indicate the occurrence of sulphonamides in some surface and mineral waters analyzed. |
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Keywords: | Column liquid chromatography LC-ESI-MS Sulphonamides Surface and drinking waters |
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