| 含1,6-二氢-6-哒嗪酮的1,3,4-噁二唑啉和噻唑烷-4-酮类化合物的合成 |
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| 引用本文： | 王彩芳,曹玲华. 含1,6-二氢-6-哒嗪酮的1,3,4-噁二唑啉和噻唑烷-4-酮类化合物的合成[J]. 有机化学, 2005, 25(10): 1287-1290 |
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| 作者姓名： | 王彩芳 曹玲华 |
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| 作者单位： | 1. 新疆大学化学化工学院,乌鲁木齐,830046
2. 新疆大学化学化工学院,乌鲁木齐,830046;南开大学元素有机化学国家重点实验室,天津,300071 |
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| 摘 要： | 以1,6-二氢-6-哒嗪酮-3-甲酰肼(1)与芳香醛反应得到相应的1,6-二氢-6-哒嗪酮-3-羰基芳香醛腙(2a～2e). 再将2a～2e与乙酸酐作用, 合环得到一系列含有1,3,4-噁二唑啉环的衍生物3a～3e; 在DMF中用HSCH2COOH合环, 得到含有4-噻唑烷酮的衍生物4a～4e. 所有化合物的结构均经元素分析, IR, 1H NMR 和MS谱得以证实.
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| 关 键 词： | 1,6-二氢-6-哒嗪酮 1,3,4-噁二唑啉 噻唑烷-4-酮 |
| 收稿时间： | 2004-11-04 |
| 修稿时间： | 2005-04-25 |
Synthesis of 1,3,4-Oxadiazoline and 4-Thiazolidinone Derivatives Containing 1,6-Dihydro-6-pyridazinone |
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| WANG,Cai-Fang,CAO,Ling-Hua. Synthesis of 1,3,4-Oxadiazoline and 4-Thiazolidinone Derivatives Containing 1,6-Dihydro-6-pyridazinone[J]. Chinese Journal of Organic Chemistry, 2005, 25(10): 1287-1290 |
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| Authors: | WANG Cai-Fang CAO Ling-Hua |
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| Affiliation: | ( College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046)( State Key Laboratory of Elemento-Organic Chemistry, Nankai Uni-versity, Tianjin 300071) |
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| Abstract: | A series of 1,3,4-oxadiazoline derivatives 3a～3e were obtained from 1,6-dihydro-6-pyridazinone-3-carbonyl aromatic aldehyde hydrozones 2a～2e by the cyclization with acetic anhydride, and 4-thiazolidinones 4a～4e were also derived from 2a～2e with mercaptoacetic acid in DMF. Their structures were established by elemental analysis, IR, 1H NMR and MS spectra. |
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| Keywords: | 1,6-dihydro-6-pyridazinone 1,3,4-oxadiazoline 4-thiazolidinone |
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