Synthesis of oxychelerythrine using lithiated toluamide-benzonitrile cycloaddition |
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Authors: | Le Thanh Nguyen Cho Won-Jea |
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Institution: | College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Kwangju, Korea. |
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Abstract: | Oxychelerythrine, benzoc]phenanthridine alkaloid, was synthesized from easily available starting toluamide 5 and benzonitrile 6 using toluamide-benzonitrile cycloaddition reaction in 6 steps. |
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