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Synthesis of new benzo[b]thieno fused ring systems via transition metal-mediated cyclisations
Authors:Johana M MbereJohn B Bremner  Brian W SkeltonAllan H White
Institution:a School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
b School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, WA 6005, Australia
Abstract:The compact synthesis of a new ring fused benzob]thieno derivative with an embedded nine-membered ring system via ring closing metathesis methodology is described. The preparation of the novel 11H-benzob]thieno2,3-c]pyrrolo2,3-a]indol-11-one via palladium-mediated oxidative cyclisation of benzob]thien-2-oyl indole derivatives is also reported.
Keywords:Ring closing metathesis  Azonino[3  4-b]benzo[b]thieno[3  2-a]isoquinolinone  Pyrrolo[2  3-a]indol-11-one  Palladium cyclisation
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