Novel gallium-mediated C3-allylation of indoles and pyrroles in aqueous media promoted by Bu4NBr |
| |
| Authors: | Dipak Prajapati Mukut Gohain Baikuntha J Gogoi |
| |
| Institution: | Medicinal Chemistry Division, Regional Research Laboratory, Jorhat 785 006, Assam, India |
| |
| Abstract: | A mild and efficient protocol for the coupling of indoles and pyrroles with allyl halides such as allyl bromide, crotyl bromide and propargyl bromide in the presence of gallium metal in a Bu4NBr-DMF-H2O system has been developed. The reaction is equally effective when cadmium is used in lieu of gallium and the corresponding 3-allyl indoles and 3-allyl pyrroles were obtained in almost comparable yields. |
| |
| Keywords: | Gallium Cadmium Aqueous media |
| 本文献已被 ScienceDirect 等数据库收录！ |
