|
|||||
|
|
Ti(NMe2)4-catalyzed Markovnikov hydroamination of alkynes in the presence of N-heterocyclic carbenes and LiN(SiMe3)2 |
|
| Authors: | Ken Takaki Sadayuki Koizumi Yuta Yamamoto Kimihiro Komeyama |
| Affiliation: | Department of Chemistry and Chemical Engineering, Graduate School of Engineering, Hiroshima University, Kagamiyama, Higashi-Hiroshima 739-8527, Japan |
| Abstract: | Intermolecular hydroamination of alkynes catalyzed by Ti(NMe2)4 was much improved with N-heterocyclic carbenes and LiN(SiMe3)2, by which high Markovnikov selectivity was attained for the coupling of nearly all alkynes and amines. |
| Keywords: | Hydroamination Alkynes Titanium catalysts N-Heterocyclic carbenes Lithium silylamides |
| 本文献已被 ScienceDirect 等数据库收录！ | |