Regioselective synthesis of polysubstituted phenol derivatives from Baylis-Hillman adducts via [3+3] annulation strategy |
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Authors: | Da Yeon Park Taek Hyeon Kim |
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Affiliation: | a Department of Chemistry and Institute of Basic Science, Chonnam National University, Gwangju 500-757, Republic of Korea b Department of Applied Chemistry, Chonnam National University, Gwangju 500-757, Republic of Korea |
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Abstract: | ![]() Polysubstituted phenol derivatives were synthesized from the acetates of Baylis-Hillman adducts and dimethyl 1,3-acetonedicarboxylate (DMAD) in a one-pot reaction via the sequential SN2′ reaction, aldol condensation, and 1,3-H shift process. |
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Keywords: | Phenols Baylis-Hillman adducts Dimethyl 1,3-acetonedicarboxylate 1,3-Dinucleophile |
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