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An effective method to use ionic liquids as reaction media for asymmetric reduction by Geotrichum candidum |
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| Authors: | Tomoko Matsuda Yusuke Yamagishi Noritaka Iwai |
| Affiliation: | a Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan b Frontier Collaborative Research Center, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan |
| Abstract: | An effective method was developed to use an enzyme in ionic liquids; the asymmetric reduction of ketones by Geotrichum candidum in ionic liquids proceeded smoothly with excellent enantioselectivity when the cell was immobilized on water-absorbing polymer containing water, while the reaction without the polymer did not proceed. |
| Keywords: | Asymmetric reduction Alcohol dehydrogenase Ionic liquid Geotrichum candidum Water-absorbing polymer |
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