Transition-metal-free access to 7-azaindoles |
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| Authors: | Dong Wang Jianyong Hu Junjie Zhao Meng Shen Yuxi Wang Peng Yu |
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| Affiliation: | China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China |
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| Abstract: | A novel method for transition-metal-free synthesis of 7-azaindoles is developed through a one-pot synthesis involving amination of pyridine N-oxides and intramolecular enamine formation. Remarkable features of the method include simple operation, mild reaction conditions, wide substrate scope, and easily accessible starting materials. |
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| Keywords: | 7-Azaindoles N-heterocycles VMLGXOHQCLWUHZ-UHFFFAOYSA-N |
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