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Synthesis and conformational analysis of (E)-9,10-dehydroepothilone B: a suggestive link between the chemistry and biology of epothilones
Authors:Yoshimura Fumihiko  Rivkin Alexey  Gabarda Ana E  Chou Ting-Chao  Dong Huajin  Sukenick George  Morel Florence F  Taylor Richard E  Danishefsky Samuel J
Affiliation:Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA.
Abstract:
Keywords:antitumor agents  conformational analysis  natural products  structure–activity relationships
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