Licamichauxiioic-A and -B acids--two ent-kaurene diterpenoids from Licania michauxii |
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| Authors: | Chaudhuri Swapan K Badisa Ramesh Babu Pilarinou Elsa Walker Evan H |
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| Institution: | Walker Cancer Research Institute, Inc, Tallahassee, Florida 32308-3729, USA. swapan97@aol.com |
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| Abstract: | Bioassay-guided fractionation allowed the isolation of two new cytotoxic ent-kaurene diterpenoids, licamichauxiioic-A and -B acids (1 and 2) from the root extract of Licania michauxii Prance (Chrysobalanaceae). They were characterized as ent-15-oxo-9(11),16-kauradien-19-oic acid (1) and ent-15-oxo-13(14),16-kauradien-19-oic acid (2) by various spectroscopic methods, in particular, 1D and 2D NMR spectra, and chemical evidence. |
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