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A photoimmobilisation strategy that maximises exploration of chemical space in small molecule affinity selection and target discovery
Authors:Dilly Suzanne J  Bell Matthew J  Clark Andrew J  Marsh Andrew  Napier Richard M  Sergeant Martin J  Thompson Andrew J  Taylor Paul C
Institution:Department of Chemistry, University of Warwick, Coventry, UK CV4 7AL.
Abstract:We show that the use of multiple photochemistries is necessary to ensure diverse immobilisation of small molecules for binding of polypeptides using phage display and antibody libraries.
Keywords:
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