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Pharmacoinformatics-based identification of transmembrane protease serine-2 inhibitors from Morus Alba as SARS-CoV-2 cell entry inhibitors |
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| Authors: | Shakya Anshul Chikhale Rupesh V. Bhat Hans Raj Alasmary Fatmah Ali Almutairi Tahani Mazyad Ghosh Surajit Kumar Alhajri Hassna Mohammed Alissa Siham A. Nagar Shuchi Islam Md Ataul |
| Affiliation: | 1.Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, Assam, 786 004, India ;2.School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR5 7TJ, UK ;3.Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia ;4.Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia ;5.Bioinformatics Research Centre, Dr. D. Y. Patil Biotechnology & Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Tathawade, Pune, India ;6.Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK ;7.School of Health Sciences, University of Kwazulu-Natal, Westville Campus, Durban, South Africa ;8.Department of Chemical Pathology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa ; |
| Abstract: | Molecular Diversity - Transmembrane protease serine-2 (TMPRSS2) is a cell-surface protein expressed by epithelial cells of specific tissues including those in the aerodigestive tract. It helps the... |
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