Discovery of inhibitors targeting protein tyrosine phosphatase 1B using a combined virtual screening approach |
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| Authors: | Zhao Dan Sun Lu Zhong Shijun |
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| Affiliation: | 1.School of Bioengineering, Dalian University of Technology, Dalian, 116024, Liaoning, People’s Republic of China
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| Abstract: | Molecular Diversity - Protein tyrosine phosphatase 1B (PTP1B) acts as a therapeutic target for type 2 diabetes. However, the major challenges of PTP1B drug discovery are the poor selectivity and... |
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