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Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity,and in silico studies on ibuprofen derivatives |
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| Authors: | Seraj Faiza Kanwal Khan Khalid Mohammed Khan Ajmal Ali Muhammad Khalil Ruqaiya Ul-Haq Zaheer Hameed Shehryar Taha Muhammad Salar Uzma Perveen Shahnaz |
| Affiliation: | 1.H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan ;2.Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam, Saudi Arabia ;3.UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, P.O. Box 33, 616, Birkat al Mauz, Nizwa, Oman ;4.Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan ;5.PCSIR Laboratories Complex, Karachi, Shahrah-e-Dr. Salimuzzaman Siddiqui, Karachi, 75280, Pakistan ;6.Institute of Marine Biotechnology, Universiti Malaysia Terengannu, 21300, Kuala Terengannu, Terengannu, Malaysia ; |
| Abstract: | Molecular Diversity - Novel ibuprofen derivatives 1–19 including ibuprofen hydrazide 1, and substituted thiourea derivatives 2–19 were synthesized and characterized by EI-MS, FAB-MS,... |
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