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Antitumor triterpene saponins from Anemone flaccida |
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| Authors: | Lan Tian Zhang Yan Wen Zhang Yoshihisa Takaishi Hong Quan Duan |
| Institution: | a School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China;b School of Pharmaceutical Sciences, Basic Medical Research Center of Tianjin, Tianjin Medical University, Tianjin 300070, China;c Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan |
| Abstract: | A new triterpenoid saponin, 3-O-(6′-butyryl)-β-d-glucopyranosyl]-28-O-α-l-rhamnopyranosyl-(1 → 4)-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranosyl] oleanolic acid, as well as three known triterpenoid saponins were isolated from the rhizomes of Anemone flaccida. Their structures were elucidated by spectroscopic methods. These compounds showed significant antitumor activities. |
| Keywords: | Anemone flaccida Triterpene saponins Cytotoxic activities |
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