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Schinarisanlactone A, a new bisnortriterpenoid from Schisandra arisanensis
Authors:Lin Yu-Chi  Lo I-Wen  Chen Shun-Ying  Lin Pi-Han  Chien Ching-Te  Chang Sui-yuan  Shen Ya-Ching
Affiliation:School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Abstract:
A novel triterpenoid, schinarisanlactone A (1), was isolated from the fruits of Schisandra arisanensis. Compound 1 possesses an unprecedented skeleton having a 5/7/7/5/7/5/6/5-fused octacyclic ring system. The structure of 1 was determined by 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. Schinarisanlactone A (1) exhibited significant anti-HIV activity.
Keywords:
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