Schinarisanlactone A, a new bisnortriterpenoid from Schisandra arisanensis |
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Authors: | Lin Yu-Chi Lo I-Wen Chen Shun-Ying Lin Pi-Han Chien Ching-Te Chang Sui-yuan Shen Ya-Ching |
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Affiliation: | School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan. |
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Abstract: | A novel triterpenoid, schinarisanlactone A (1), was isolated from the fruits of Schisandra arisanensis. Compound 1 possesses an unprecedented skeleton having a 5/7/7/5/7/5/6/5-fused octacyclic ring system. The structure of 1 was determined by 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. Schinarisanlactone A (1) exhibited significant anti-HIV activity. |
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