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Ruthenium(II) polypyridyl complexes as carriers for DNA delivery
Authors:Bhat Satish S  Kumbhar Avinash S  Kumbhar Anupa A  Khan Ayesha  Lönnecke Peter  Hey-Hawkins Evamarie
Institution:Department of Chemistry, University of Pune, Pune- 411007, India.
Abstract:Two novel water soluble ruthenium(II) complexes Ru(bpy)(2)(bqbg)](2+) and Ru(phen)(2)(bqbg)](2+) have been structurally characterized and their DNA condensation activity, cytotoxicity, and cellular uptake studies of DNA condensates as potential non-viral DNA carriers were evaluated.
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