Metal-free synthesis of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles via microwave-assisted synthesis pathway |
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Authors: | Truong Thanh Tung Luong Xuan Huy |
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Institution: | 1. Faculty of Pharmacy, PHENIKAA University, Hanoi, Vietnam;2. PHENIKAA Institute for Advanced Study (PIAS), PHENIKAA University, Hanoi, Vietnamtung.truongthanh@phenikaa-uni.edu.vn;4. PHENIKAA Institute for Advanced Study (PIAS), PHENIKAA University, Hanoi, Vietnam |
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Abstract: | AbstractA simple, efficient, and metal-free methodology for the preparation of 2-mercaptobenzothiazole and derivatives in excellent yields via microwave-assisted pathway is reported. Our condition provides a convenient protocol for the synthesis of a diverse collection of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles with a very simple purification process. This report provides an alternative protocol for fast access to the wide range of compounds for sequence synthesis and biological studies. |
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Keywords: | microwave-assisted synthesis metal-free 2-mercaptobenzothiazole |
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