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| Inhibition of the Crystal Growth and Aggregation of Calcium Oxalate by Algae Sulfated Polysaccharide In-vitro | |
| 引用本文： | Xiu Mei WU Jian Ming OUYANG Sui Ping DENG Ying Zhou CEN. Inhibition of the Crystal Growth and Aggregation of Calcium Oxalate by Algae Sulfated Polysaccharide In-vitro[J]. 中国化学快报, 2006, 17(1): 97-100 |
| 作者姓名： | Xiu Mei WU Jian Ming OUYANG Sui Ping DENG Ying Zhou CEN |
| 作者单位： | Xiu Mei WU1，Jian Ming OUYANG1，2，Sui Ping DENG1，Ying Zhou CEN2 1Institute of Biomineralization and Lithiasis Research，2Department of Chemistry，Jinan University，Guangzhou 510632 |
| 基金项目： | Acknowledgments This research work was granted by the National Natural Science Foundation of China （20471024） and the Project-sponsored by SRF for R0CS, SEM and the Key project of Natural Science Foundation of China （20031010）. |
| 摘 要： | Kidney stone disease causes substantial suffering and occasional renal failure. The content of calcium oxalate (CaOxa) is up to 70-80% in the stones1,2. However, the mechanism of the formation of urinary stones is not yet clearly understood and the questi… |
| 关 键 词： | 草酸钙 硫酸多醣 尿结石 海藻 提取 X射线衍射分析 晶体生长 |
| 收稿时间： | 2005-05-11 |
Inhibition of the Crystal Growth and Aggregation of Calcium Oxalate by Algae Sulfated Polysaccharide In-vitro |
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| Xiu Mei WU,Jian Ming OUYANG,Sui Ping DENG,Ying Zhou CEN. Inhibition of the Crystal Growth and Aggregation of Calcium Oxalate by Algae Sulfated Polysaccharide In-vitro[J]. Chinese Chemical Letters, 2006, 17(1): 97-100 | |
| Authors: | Xiu Mei WU Jian Ming OUYANG Sui Ping DENG Ying Zhou CEN |
| Abstract: | The influence of sulfated polysaccharide (SPS) isolated from marine algae Sargassum fusiforme on the morphology and phase compositions of urinary crystal calcium oxalate was investigated in vitro by means of scanning electron microscopy and X-ray diffraction. SPS maybe is a potential inhibitor to CaOxa urinary stones by inhibiting the growth of calcium oxalate monohydrate (COM), preventing the aggregation of COM, and inducing the formation of calcium oxalate dihydrate (COD) crystals. |
| Keywords: | Calcium oxalate sulfated polysaccharide urinary stone. |
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